| ncRNA name | mmu-miR-466d-3p |
| ncRNA Category | miRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Mus musculus |
| Tissues/Cell_line | retinas |
| Methods | microarray, qRT-PCR, chromatin immunoprecipitation (CHIP) |
| Expression pattern | differentially expressed |
| Functional description | 54 miRNAs were differentially expressed between Nr2e3 rd7/rd7 and C57BL6/J mice with a minimum 2-fold change and a p value of p < 0.001.We discovered multimodal regulation by miRNA, NHRs, and epigenetic factors of three miRNAs (miR-466, miR1187, and miR-710) and two genes (Ell2 and Entpd1) that are also associated with AMD. |
| PubMed ID | 28386079 |
| Year | 2017 |
| Title | Multimodal Regulation Orchestrates Normal and Complex Disease States in the Retina. |
| Drug-related ncRNA | NO |
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